Treatment of temporomandibular joint osteoarthritis using dental stem cell secretome

Perawatan temporomandibular joint osteoarthritis menggunakan dental stem cell secretome

  • Nurul Auliya Prosthodontic Department, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia
  • Muhammad Ikbal Prosthodontic Department, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia
  • Eri Hendra Jubhari Prosthodontic Department, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia
Keywords: dental, osteoarthritis, secretome, stem cells, temporomandibular joint

Abstract

Temporomandibular joint osteoarthritis (TMJ-OA) is caused by disc dislocation, trauma, functional overload, and developmental abnormalities. One of the effectively used TMJ-OA treatments is dental stem cell secretome (DSECR); it has shown promising po-tential in cartilage regeneration. This review analyses DSECR as having the potential to halt or suppress the progression of TMJ-OA. It was concluded that treatment using DSECR promoted regeneration and repair of chemically induced TMJ-OA, indicating that DSECR has great potential to be a cell-free therapeutic approach.

Published
2025-04-01