Effectiveness of inhibition of telang flower (Clitoria ternatea L.) against the growth of Candida albicans

Efektivitas daya hambat bunga telang (Clitoria ternatea L.) terhadap pertumbuhan Candida albicans

Abstract

Oral candidiasis is the most common opportunistic infection affecting the oral mucosa. In the majority of cases, the lesions are caused by Candida albicans. Various types of antifungal drugs have been widely produced and sold in the market to treat Can-didiasis, but these drugs have side effects. One of the plants that can be cultivated as an ornamental and medicinal plant is te-lang flower (Clitoria ternatea L.). It is known that the inhibition of telang flowers against C.albicans is caused by anthocyanins. This experimental study was designed with post-test only control group. Statistical tests with Kruskal-Wallis showed signifi-cant differences in the effectiveness of telang flower extract concentrations of 50%, 75%, 100% in killing C.albicans colonies. Mann Whitney test did not get a significant difference in the concentration of 50%, 75%, 100% telang flower extract in killing C. albicans; both on SDA media. The concentration of telang flower that continues to be increased has decreased in effectiveness. It is concluded that the higher the concentration of the diffusion power of the extract into the media decreases so that the lower the solubility.