Antibacterial activity of longan seed extract (Dimocarpus longan L.) to P.gingivalis
Aktivitas antibakteri ekstrak biji kelengkeng (Dimocarpus longan L.) terhadap P.gingivalis
Abstract
Longan (Dimocarpus longan L.) is a plant that has potential as an antibacterial. Longan seeds are part of the longan plant which contains antibacterial compounds in the form of phenolics, tannins, flavonoids, and triterpenoids. This research is aimed to deter-mine the antibacterial effect of longan seeds on the bacterium Porphyromonas gingivalis ATCC 332277 which causes chronic periodontitis by calculating the average diameter of the inhibition zone. This research was conducted using experimental labora-tory methods with groups at concentrations of 3.125%, 6.25%, 12.5%, 25%, 50%, 75%, 100%. In comparison, chlorhexidine 0,2% as a positive control and DMSO 10% as a negative control. Based on the well diffusion method, the results showed that in the experimental group, a concentration of 100% resulted in a 10.07 mm zone of inhibition but not greater than chlorhexidine 0.2% which has 11.94 mm. At the same time, the smallest inhibition zone was produced by longan seeds with 25% extract which was 3.15 mm. It is concluded that there is an effect of longan seed extract on inhibiting the growth of P.gingivalis bacteria.
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